Precalcification treatment improves the surface bioactivity of tantalum

Because of its good biocompatibility, excellent corrosion resistance, mechanical properties and easy processing, tantalum and its alloys have been widely paid attention in the field of biological medicine, especially in orthopedics. Many scholars at home and abroad have reported the successful application of porous tantalum in the treatment of femoral head necrosis, hip replacement, spinal interbody fusion, repair of bone defects and other fields. However, tantalum is a kind of bioinert material. After being implanted into the human body, it is easy to coat and form fibrous tissue around it, so it cannot form a stable chemical combination with the surrounding bone tissue, and it is easy to cause problems such as aseptic loosening. Among the biological implant materials, only some ceramic materials, such as bioglass and apatite, can directly form stable osseous bond with human bone. However, due to the poor fracture toughness of ceramics, they cannot replace the defective bone tissue to bear too much load pressure after implantation in human body, and are prone to degradation. Therefore, using the mechanical properties of metal implant materials to improve their surface biological activity is a hot research field. Some researchers proposed to prepare a bioactive coating on the surface of tantalum metal to form a chemical combination with the surrounding bone tissue so as to improve the stability of tantalum implants.